Busia District is a district in the Eastern region of Uganda.

Busia District borders Tororo District to the north, Busia County, Kenya to the east, Namayingo District to the south, and to the south-west, and Bugiri District to the west. Busia, Uganda, the site of the district headquarters, is approximately 35 km (22 mi) by road south of Tororo, the nearest large town.

Busia district is made up of small administrative offices for example counties, Sub counties and Parishes as discussed below.

Sub counties and their parishes:

Sub counties and their parishes include the following as discussed below:

Sub counties and their parishes:

At the 1991 national population census, the population in the district was estimated at 163,600. In 2002, the national census estimated the population at 225,000. In 2012, the mid-year population was estimated at 297,600. in 2014 it was 323,662 and 2024 it was 412,671 .

Notable people from Busia District include: