Quark–gluon plasma (QGP or quark soup) is an interacting localized assembly of quarks and gluons at thermal (local kinetic) and (close to) chemical (abundance) equilibrium. The word plasma signals that free color charges are allowed. In a 1987 summary, Léon Van Hove pointed out the equivalence of the three terms: quark gluon plasma, quark matter and a new state of matter. Since the temperature is above the Hagedorn temperature—and thus above the scale of light u,d-quark mass—the pressure exhibits the relativistic Stefan–Boltzmann format governed by temperature to the fourth power (${\displaystyle T^{4}}$) and many practically massless quark and gluon constituents. It can be said that QGP emerges to be the new phase of strongly interacting matter which manifests its physical properties in terms of nearly free dynamics of practically massless gluons and quarks. Both quarks and gluons must be present in conditions near chemical (yield) equilibrium with their color charge open for a new state of matter to be referred to as QGP.

In the Big Bang theory, quark–gluon plasma filled the entire Universe before matter as we know it was created. Theories predicting the existence of quark–gluon plasma were developed in the late 1970s and early 1980s. Discussions around heavy ion experimentation followed suit, and the first experiment proposals were put forward at CERN and BNL in the following years. Quark–gluon plasma was detected for the first time in the laboratory at CERN in the year 2000.

Quark–gluon plasma is a state of matter in which the elementary particles that make up the hadrons of baryonic matter are freed of their strong attraction for one another under extremely high energy densities. These particles are the quarks and gluons that compose baryonic matter. In normal matter quarks are confined; in the QGP quarks are deconfined. In classical quantum chromodynamics (QCD), quarks are the fermionic components of hadrons (mesons and baryons) while the gluons are considered the bosonic components of such particles. The gluons are the force carriers, or bosons, of the QCD color force, while the quarks by themselves are their fermionic matter counterparts.

Quark–gluon plasma is studied to recreate and understand the high energy density conditions prevailing in the Universe when matter formed from elementary degrees of freedom (quarks, gluons) at about 20 μs after the Big Bang. Experimental groups are probing over a 'large' distance the (de)confining quantum vacuum structure, which determines prevailing form of matter and laws of nature. The experiments give insight to the origin of matter and mass: the matter and antimatter is created when the quark–gluon plasma 'hadronizes' and the mass of matter originates in the confining vacuum structure.

QCD is one part of the modern theory of particle physics called the Standard Model. Other parts of this theory deal with electroweak interactions and neutrinos. The theory of electrodynamics has been tested and found correct to a few parts in a billion. The theory of weak interactions has been tested and found correct to a few parts in a thousand. Perturbative forms of QCD have been tested to a few percent. Perturbative models assume relatively small changes from the ground state, i.e. relatively low temperatures and densities, which simplifies calculations at the cost of generality. In contrast, non-perturbative forms of QCD have barely been tested. The study of the QGP, which has both a high temperature and density, is part of this effort to consolidate the grand theory of particle physics.

The study of the QGP is also a testing ground for finite temperature field theory, a branch of theoretical physics which seeks to understand particle physics under conditions of high temperature. Such studies are important to understand the early evolution of our universe: the first hundred microseconds or so. It is crucial to the physics goals of a new generation of observations of the universe (WMAP and its successors). It is also of relevance to Grand Unification Theories which seek to unify the three fundamental forces of nature (excluding gravity).

The generally accepted model of the formation of the Universe states that it happened as the result of the Big Bang. In this model, in the time interval of 10⁻¹⁰–10⁻⁶ s after the Big Bang, matter existed in the form of a quark–gluon plasma. It is possible to reproduce the density and temperature of matter existing of that time in laboratory conditions to study the characteristics of the very early Universe. So far, the only possibility is the collision of two heavy atomic nuclei accelerated to energies of more than a hundred GeV. Using the result of a head-on collision in the volume approximately equal to the volume of the atomic nucleus, it is possible to model the density and temperature that existed in the first instants of the life of the Universe.

A plasma is matter in which charges are screened due to the presence of other mobile charges. For example: Coulomb's law is suppressed by the screening to yield a distance-dependent charge, ${\displaystyle Q\rightarrow Qe^{-r/\alpha }}$, i.e., the charge Q is reduced exponentially with the distance divided by a screening length α. In a QGP, the color charge of the quarks and gluons is screened. The QGP has other analogies with a normal plasma. There are also dissimilarities because the color charge is non-abelian, whereas the electric charge is abelian. Outside a finite volume of QGP the color-electric field is not screened, so that a volume of QGP must still be color-neutral. It will therefore, like a nucleus, have integer electric charge.