Sensitization (immunology)

In immunology, the term sensitization is used for the following concepts:

Those particles themselves are biologically inactive except for serving as antigens against the primary antibodies or as carriers of the antigens. When antibodies are used in the preparation, they are bound to the erythrocyte or particles in their Fab regions. Thus the step follows requires the secondary antibodies against those primary antibodies, that is, the secondary antibodies must have binding specificity to the primary antibodies including to their Fc regions.