Patsy O'Connell Sherman was born in Minneapolis, Minnesota. From a young age, she demonstrated a keen interest in science and problem-solving, laying the foundation for her future career as a chemist.

During her early education, Patsy excelled in science and mathematics, fostering a deep-seated curiosity about the world around her. This early passion was instrumental in shaping her pursuit of a scientific career.

Patsy Sherman earned a dual Bachelor of Science degree in Chemistry and Mathematics from Gustavus Adolphus College. This strong academic foundation provided her with the necessary skills and knowledge to embark on a career in industrial chemistry.

After graduating, Patsy joined the 3M Company (Minnesota Mining and Manufacturing) as a chemist. This marked the beginning of her long and impactful career, where she would make her most significant contribution to the field of chemistry.

While working on a project to develop a rubber for aircraft fuel lines, Patsy and her colleague Samuel Smith accidentally spilled a fluorochemical synthetic latex on a canvas tennis shoe. They were unable to remove the spill, but they noticed that the area repelled water, oil and other liquids. This accidental discovery was the basis of Scotchgard.

Following the accidental discovery, Patsy and Samuel dedicated themselves to developing and refining the formula. They worked on adapting the fluorochemical polymer to be used on various surfaces, including fabrics and carpets, ultimately creating a product that was effective, durable, and safe for consumer use.

Patsy O'Connell Sherman and Samuel Smith were granted a patent for Scotchgard. This patent secured their intellectual property and paved the way for 3M to market and sell the revolutionary stain repellent and durable water repellent.

Throughout her career at 3M, Patsy continued to contribute to various research and development projects. She remained active in the scientific community, mentoring other scientists and promoting innovation within the company.

In recognition of her groundbreaking invention of Scotchgard, Patsy O'Connell Sherman was inducted into the National Inventors Hall of Fame. This prestigious honor highlighted the significance of her contribution to science and technology.

Patsy O'Connell Sherman passed away on February 11, 2008, at the age of 77. Her legacy as a brilliant chemist and co-inventor of Scotchgard continues to inspire scientists and innovators around the world.