Laos at the 1980 Summer Olympics

Men's 100 metres

• Soutsakhone Somninhom

• Heat — 11.69 (→ did not advance)

Men's 200 metres

• Sitthixay Sacpraseuth

• Heat — 24.28 (→ did not advance)

Men's 800 metres

• Vongdeuane Phongsavanh

• Heat — 2:05.5 (→ did not advance)

Men's 20 km Walk

• Thipsamay Chanthaphone

• Final — 2:20:22.0 (→ 25th place)

Women's 100 metres

• Seuth Khampa

• Heat — 14.62 (→ did not advance)

• Boualong Boungnavong
• Vongdeuane Phongsavanh

Men's Light Flyweight (48 kg)

• Singkham Phongprathith^{[citation needed]}
  1. First Round — Lost to Pedro Manuel Nieves (Venezuela) after referee stopped contest in first round

Men's Bantamweight (54 kg)

• Souneat Ouphaphone
  1. First Round — Bye
  2. Second Round — Lost to Fayez Zaghloul (Syria) on points (5-0)

Men's Featherweight (57 kg)

• Takto Youtiya Homrasmy
  1. First Round — Bye
  2. Second Round — Lost to Winfred Kabunda (Zambia) after referee stopped contest in first round

Men's Lightweight (60 kg)

• Bounphisith Songkhamphou
  1. First Round — Lost to Kazimierz Adach (Poland) after referee stopped contest in second round

Men's Light-Welterweight (63.5 kg)

• Kampanath
  1. First Round — Lost to Farez Halabi (Syria) on points (2-3)