1-Indanone is the organic compound with the formula C₆H₄(CH₂)₂CO. It is one of two isomeric benzocyclopentanones, the other being 2-indanone. It is a colorless solid. 1-Indanone is a substrate for the enzyme indanol dehydrogenase.

It is prepared by oxidation of indane or indene. It can also be prepared by cyclization of phenylpropionic acid.

1-Indanone is an intermediate in the synthesis of a variety of pharmaceutical drugs including 2-aminoindane (using beta-keto-oxime formation with isoamylnitrite followed by reduction), drinidene, pirandamine, pyrophendane & rasagiline.

1-Indanol can be produced by hydride reduction of 1-indanone.