The 1958 NCAA University Division baseball tournament was played at the end of the 1958 NCAA University Division baseball season to determine the national champion of college baseball. The tournament concluded with eight teams competing in the College World Series, a double-elimination tournament in its twelfth year. Eight regional districts sent representatives to the College World Series with preliminary rounds within each district serving to determine each representative. These events would later become known as regionals. Each district had its own format for selecting teams, resulting in 26 teams participating in the tournament at the conclusion of their regular season, and in some cases, after a conference tournament. The College World Series was held in Omaha, NE from June 13 to June 19. The twelfth tournament's champion was Southern California, coached by Rod Dedeaux. The Most Outstanding Player was Bill Thom of Southern California.

Brigham Young University withdrew from district. Colorado State College was selected as District 7 representative in the College World Series.

The following players were members of the All-Tournament Team.