The 2016 Rugby League Four Nations tournament (known as the 2016 Ladbrokes Four Nations, for sponsorship purposes) was the fifth and final staging of the Rugby League Four Nations tournament and was played in England in October and November. The series was contested by Australia, England, New Zealand and Scotland, who qualified for their first Four Nations by winning the 2014 European Cup. The final was played on 20 November, with Australia winning its third tournament, defeating New Zealand.

The 2016 tournament is the fifth Four Nations series to be planned before the 2017 Rugby League World Cup, with the venues rotating between Europe and the South Pacific.

In addition to automatic inclusions Australia, England and New Zealand, Scotland qualified for the tournament by defeating France in the final of the 2014 European Cup.

England have previously co-hosted tournaments with other European nations and the Rugby Football League (RFL) planned to take a game up into Scotland but backed down and decided to take games to other venues.

The redeveloped 54,074 capacity Anfield Stadium hosted the Four Nations Final. This was the first time in 19 years the venue had held a rugby league match. Three rugby league games have been played at Anfield before. The final was the first ever international rugby league match held at the venue.

* Denotes winner of tournament event.

The games were played at the following venues in England. The tournament final was played at Anfield.

Before the series, Australia and New Zealand organised to play the first ever International rugby league test-match in Perth, Scotland took on a Cumbrian rugby league team and England took on France in Avignon.