The 2018 O'Reilly Auto Parts 500 was a Monster Energy NASCAR Cup Series race held on April 8, 2018, at Texas Motor Speedway in Fort Worth, Texas. Contested over 334 laps on the 1.5-mile (2.4 km) intermediate quad-oval, it was the seventh race of the 2018 Monster Energy NASCAR Cup Series season.

Texas Motor Speedway is a speedway located in the northernmost portion of the U.S. city of Fort Worth, Texas – the portion located in Denton County, Texas. The track measures 1.5 miles (2.4 km) around and is banked 24 degrees in the turns, and is of the oval design, where the front straightaway juts outward slightly. The track layout is similar to Atlanta Motor Speedway and Charlotte Motor Speedway (formerly Lowe's Motor Speedway). The track is owned by Speedway Motorsports, Inc., the same company that owns Atlanta and Charlotte Motor Speedways, as well as the short-track Bristol Motor Speedway.

Kurt Busch was the fastest in the first practice session with a time of 27.523 seconds and a speed of 196.200 mph (315.753 km/h).

Kurt Busch scored the pole for the race with a time of 27.360 and a speed of 197.368 mph (317.633 km/h) after only one round of qualifying was completed due to lightning in the area.

Daniel Suárez was the fastest in the second practice session with a time of 27.136 seconds and a speed of 198.998 mph (320.256 km/h).

Jimmie Johnson was the fastest in the final practice session with a time of 27.253 seconds and a speed of 198.143 mph (318.880 km/h).

Stage 1 Laps: 85

Stage 2 Laps: 85