| 2018 RBC Pro Challenge | |
|---|---|
| Date | 29 October–4 November |
| Edition | 2nd |
| Category | ITF Women's Circuit |
| Prize money | $80,000 |
| Surface | Hard |
| Location | Tyler, United States |
| Champions | |
| Singles | |
 Whitney Osuigwe | |
| Doubles | |
| Nicole Gibbs / Asia Muhammad | |
The 2018 RBC Pro Challenge was a professional tennis tournament played on outdoor hard courts. It was the second edition of the tournament and was part of the 2018 ITF Women's Circuit. It took place in Tyler, United States, on 29 October–4 November 2018.
| Country | Player | Rank1 | Seed |
|---|---|---|---|
 SUI
|
Belinda Bencic | 37 | 1 |
| USA
|
Madison Brengle | 89 | 2 |
 HUN
|
Fanny Stollár | 127 | 3 |
| USA
|
Jessica Pegula | 129 | 4 |
| USA
|
Claire Liu | 139 | 5 |
| USA
|
Nicole Gibbs | 143 | 6 |
| USA
|
Kristie Ahn | 145 | 7 |
| USA
|
Christina McHale | 153 | 8 |
The following players received a wildcard into the singles main draw:
The following player received entry using a protected ranking:
Elizabeth Halbauer
Nadia PodoroskaThe following player received entry using a junior exempt:
The following players received entry from the qualifying draw:
Whitney Osuigwe def. 
Beatriz Haddad Maia, 6–3, 6–4 Nicole Gibbs / Asia Muhammad def. Desirae Krawczyk / 
Giuliana Olmos, 3–6, 6–3, [14–12]
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