The 2024 LTP Men's Open was a professional tennis tournament played on hardcourts. It was the third edition of the tournament which was part of the 2024 ATP Challenger Tour. It took place in Charleston, United States between September 23 and September 29, 2024.

The following players received wildcards into the singles main draw:

The following players received entry into the singles main draw as special exempts:

The following players received entry from the qualifying draw:

The following player received entry as a lucky loser: