7,N,N-TMT
7,N,N-TMT
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945164

7,N,N-TMT

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945164

7,N,N-TMT

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7,N,N-TMT

7,N,N-trimethyltryptamine (7,N,N-TMT), also known as 7-methyl-DMT, is a tryptamine derivative which acts as an agonist of 5-HT2 receptors. In animal tests, both 7-TMT and its 5-methoxy derivative 5-MeO-7-TMT produced behavioural responses similar to those of psychedelic drugs such as DMT, but the larger 7-ethyl and 7-bromo derivatives of DMT did not produce psychedelic responses despite having higher 5-HT2 receptor affinity in vitro (cf. DOBU, DOAM). 7-TMT also weakly inhibits reuptake of serotonin but with little effect on dopamine or noradrenaline reuptake.

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