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Aquaporin-5
Aquaporin-5 (AQP-5) is a protein that in humans is encoded by the AQP5 gene.
Aquaporin-5 (AQP-5) is a water channel protein. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). Aquaporin-5 plays a role in the generation of saliva, tears and pulmonary secretions. AQP0, AQP2, AQP5, and AQP6 are closely related and all map to 12q13.
AQP-5 features a homotetrameric structure embedded in the cell membrane with the center of each monomer acting as a water pore. Each monomer structure is a transmembrane protein which have an asparagine–proline–alanine (NPA) hydrophobic residue embedded in the membrane of the cell. The NPA residue plays a role in water and solute permeability across the membrane of the cell.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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Aquaporin-5
Aquaporin-5 (AQP-5) is a protein that in humans is encoded by the AQP5 gene.
Aquaporin-5 (AQP-5) is a water channel protein. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). Aquaporin-5 plays a role in the generation of saliva, tears and pulmonary secretions. AQP0, AQP2, AQP5, and AQP6 are closely related and all map to 12q13.
AQP-5 features a homotetrameric structure embedded in the cell membrane with the center of each monomer acting as a water pore. Each monomer structure is a transmembrane protein which have an asparagine–proline–alanine (NPA) hydrophobic residue embedded in the membrane of the cell. The NPA residue plays a role in water and solute permeability across the membrane of the cell.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.