Apolipoprotein A-II
Apolipoprotein A-II
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Apolipoprotein A-II

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Apolipoprotein A-II

Apolipoprotein A-II is a protein that in humans is encoded by the APOA2 gene. It is the second most abundant protein of the high density lipoprotein particles. The protein is found in plasma as a monomer, homodimer, or heterodimer with apolipoprotein D. ApoA-II regulates many steps in HDL metabolism, and its role in coronary heart disease is unclear. Defects in this gene may result in apolipoprotein A-II deficiency or hypercholesterolemia.

ApoA-II has been shown to interact with phospholipid transfer protein.

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