Brasenose College (BNC) is one of the constituent colleges of the University of Oxford in England. Founded in 1509 by Bishop of Lincoln William Smyth and Sir Richard Sutton, it traces its origins to an eponymous 13th-century medieval academic hall.

In 2023, Brasenose placed second in the Norrington Table (an unofficial measure of performance in undergraduate degree examinations). In a recent Oxford Barometer Survey, Brasenose's undergraduates registered 98% overall satisfaction. In recent years, around 80% of the UK undergraduate intake have been from state schools.

Brasenose is home to one of the oldest rowing clubs in the world, Brasenose College Boat Club. Notable alumni include two British prime ministers (Henry Addington and David Cameron), two Australian prime ministers (Sir John Gorton and Malcolm Turnbull), and three Nobel Prize winners (J. Michael Kosterlitz, Richard Robson, and Sir William Golding).

The history of Brasenose College, Oxford stretches back to 1509, when the college was founded on the site of Brasenose Hall, a medieval academic hall whose name is first mentioned in 1279.

Its name is believed to derive from the name of a brass or bronze knocker that adorned the hall's door and had a prominent nose, hence "Brass-Nose which became "Brasenose", see the picture on the left.

The college was associated with Lancashire and Cheshire, the county origins of its two founders – the Bishop of Lincoln, William Smyth and Sir Richard Sutton – a link which was maintained strongly until the latter half of the twentieth century. The first principals navigated Brasenose, with its Catholic sympathisers, through the Reformation and continuing religious reforms.

Most of Brasenose favoured the Royalist side during the English Civil War, although it produced notable generals and clergy on both sides.

The library and chapel were completed in the mid-17th century, despite Brasenose suffering continuing financial problems.