Collagen, type XXVIII, alpha 1

COL28A1
Identifiers
Aliases	COL28A1, COL28, collagen type XXVIII alpha 1, collagen type XXVIII alpha 1 chain
External IDs	OMIM: 609996; MGI: 2685312; HomoloGene: 66345; GeneCards: COL28A1; OMA:COL28A1 - orthologs
Gene location (Human) Chr. Chromosome 7 (human)[1] Band 7p21.3 Start 7,356,203 bp[1] End 7,535,873 bp[1]
Gene location (Mouse) Chr. Chromosome 6 (mouse)[2] Band 6|6 A1 Start 7,997,808 bp[2] End 8,192,617 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in sural nerve trigeminal ganglion spinal ganglia right uterine tube bronchial epithelial cell olfactory zone of nasal mucosa epithelium of colon parotid gland muscle layer of sigmoid colon anterior pituitary Top expressed in spermatocyte spermatid morula zygote esophagus primary oocyte quadriceps femoris muscle lip secondary oocyte urinary bladder More reference expression data BioGPS n/a
Gene ontology Molecular function peptidase inhibitor activity serine-type endopeptidase inhibitor activity extracellular matrix structural constituent extracellular matrix structural constituent conferring tensile strength Cellular component extracellular region basement membrane collagen endoplasmic reticulum lumen extracellular matrix extracellular space collagen-containing extracellular matrix Biological process negative regulation of peptidase activity cell adhesion negative regulation of endopeptidase activity extracellular matrix organization Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 340267 213945 Ensembl ENSG00000215018 ENSMUSG00000068794 UniProt Q2UY09 Q2UY11 RefSeq (mRNA) NM_001037763 NM_001037865 RefSeq (protein) NP_001032852 NP_001032954 Location (UCSC) Chr 7: 7.36 – 7.54 Mb Chr 6: 8 – 8.19 Mb PubMed search [3] [4]
Wikidata
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Collagen, type XXVIII, alpha 1 also known as COL28A1 is a protein that in humans is encoded by the COL28A1 gene.^[5] This protein belongs to a class of collagens that contain von Willebrand factor type A domains.^[6] The protein is encoded by the COL28A1 gene which contains 45 exons and is found of the p arm of chromosome 7.^[6]

1. ^ ^{a b c} GRCh38: Ensembl release 89: ENSG00000215018 – Ensembl, May 2017
2. ^ ^{a b c} GRCm38: Ensembl release 89: ENSMUSG00000068794 – Ensembl, May 2017
3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. ^ Veit G, Kobbe B, Keene DR, Paulsson M, Koch M, Wagener R (Feb 2006). "Collagen XXVIII, a novel von Willebrand factor A domain-containing protein with many imperfections in the collagenous domain". The Journal of Biological Chemistry. 281 (6): 3494–504. doi:10.1074/jbc.M509333200. PMID 16330543.
6. ^ ^{a b} "COL28A1 collagen, type XXVIII, alpha 1 [Homo sapiens (human)] - Gene - NCBI". www.ncbi.nlm.nih.gov. Retrieved 2015-09-25.

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