Cytochrome b5, type A
Cytochrome b5, type A
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Cytochrome b5, type A

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Cytochrome b5, type A

Cytochrome b5, form A (gene name CYB5A), is a human microsomal cytochrome b5.

Cytochrome b5 is a membrane bound hemoprotein which functions as an electron carrier for several membrane bound oxygenases. It has two isoforms produced by alternative splicing. Isoform 1 is bound to the cytoplasmic side of the endoplasmic reticulum. It has a C-terminal transmembrane alpha-helix. Isoform 2 was found in cytoplasm. Defects in CYB5A are the cause of type IV hereditary methemoglobinemia.

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