Zeta-Jones supports various charities, including those focused on children's health, cancer research, and education. She often participates in fundraising events and raises awareness for these causes.

Zeta-Jones becomes involved with the NSPCC (National Society for the Prevention of Cruelty to Children), a UK-based charity dedicated to protecting children. She supports their efforts to prevent child abuse.

Zeta-Jones becomes a patron of the Children's Hospital for Wales, supporting their efforts to provide specialized medical care for children in Wales.

Having been open about her own struggles with bipolar II disorder, Zeta-Jones becomes an advocate for mental health awareness. She speaks publicly about her experiences to help reduce stigma and encourage others to seek treatment.