Centennial Campus is a research park and educational campus owned and operated by North Carolina State University in Raleigh, North Carolina, United States. Composed of two locations, the 1,334 acres (5.4 km²) property provides office and lab space for corporate, governmental and not-for-profit entities, in addition to providing space for 75 university research centers, institutes, laboratories and departmental units. Currently, 5,000,000 sq ft (460,000 m²) of constructed space has been built. Upon completion, Centennial Campus is anticipated to have 9,000,000 sq ft (840,000 m²) of constructed space.

In addition to holding office and lab buildings, Centennial Campus also has the Lonnie Poole Golf Course, a public fishing pier and lake (Lake Raleigh), greenway, disc golf course, and residential living options, including townhomes, apartments and condos. Centennial Campus is also home to the Dorothy and Roy Park Alumni Center.

Centennial Campus is located just south of NC State's main campus in Raleigh, bordering Avent Ferry Road and Centennial Parkway. The campus is approximately 15 miles (24 km) east of Research Triangle Park and Raleigh-Durham International Airport, and 5 minutes from downtown Raleigh.

The first tract of land 385 acres (1.6 km²) was turned over to NC State University in 1984 by North Carolina Governor James B. Hunt, Jr. The land was originally part of the state-owned mental health facility, Dorothea Dix Hospital. Another 455 acres (1.8 km²) was turned over to NC State in 1985 by Governor James G. Martin. After the development of a Master Plan under the direction of Claude McKinney, dean of the School of Design, the first building was completed and occupied in 1989. The first corporate tenant, ABB, moved in during 1991. That same year, the College of Textiles moved to Centennial Campus. In 2000, the Centennial Biomedical Campus was established. Beginning in 2002, the College of Engineering began to relocate to Centennial Campus

The James B. Hunt Jr. Library, which was completed in late 2012 and opened in January 2013, is the main library for Centennial Campus. The 200,000 sq ft (19,000 m²) Hunt Library, named for former N.C. Governor James B. Hunt Jr., was proposed partially to alleviate overcrowded conditions in university library spaces. It also houses an automated book retrieval system, called the "BookBot," and the Institute for Emerging Issues (IEI), a public-policy organization. The NC General Assembly approved funding for the new library in 2007.

Also under construction is the 110,000 sq ft (10,000 m²) Randall B. Terry, Jr. Companion Animal Veterinary Medical Center. The Keystone Centennial Science Center, a 72,000 sq ft (6,700 m²) lab and office space complex, as well as Engineering Building III, were completed during the summer of 2010.

Buildings on Centennial Campus are funded in four ways: (1) state-appropriated funds; (2) university revenue bonds; (3) private development and (4) private fund raising.

Centennial Campus was named “Outstanding Research Park” in 2007 by the Association of University Research Parks (AURP) and has received worldwide recognition for its leadership in innovation through public-private partnerships.