Christian Brothers College (CBC) is a private Catholic school in Adelaide, South Australia. It was founded by a group of Irish Christian Brothers in 1878. It is now one of three Christian Brothers schools in the state, along with St Paul's College, Adelaide and Rostrevor College. Like the other colleges, the influence of the original Christian Brothers has waned, and it is now administered by EREA. The last brother left the school in 2007.

CBC is predominantly a secondary school, although it has a primary school campus, with a combined student population of approximately 970 (as of 2024).

Christian Brothers College has six houses. Each house is named after a person or place connected with the story of Edmund Ignatius Rice.

Upon commencement at the college, each student is assigned to one of the six houses:

In the senior campus for Christian Brothers College, students can nominate to be a leader of their house.

In May 2014, the Royal Commission into Institutional Responses to Child Sex Abuse heard that a long line of Christian Brothers accused of child sex abuse were transferred to Christian Brothers College in Adelaide from 1919 to 1969.

On 12 December 2018, a former teacher at Christian Brothers College was sentenced to at least two years in prison for having a sexual relationship with one of her students over a two-month period in 2016.