Condamine is a rural town and locality in the Western Downs Region, Queensland, Australia. In the 2021 census, the locality of Condamine had a population of 294 people.

Condamine is claimed to be the location of the invention of the Condamine Bell, a small bell made from sheet metal used to locate herds of cattle.

The town is 333 kilometres (207 mi) north west of the state capital Brisbane and 34 kilometres (21 mi) south from the town of Miles, in the Western Downs Region local government area. It is located in the centre of the locality.

The Leichhardt Highway traverses the locality from north to south passing through the town, and the Roma-Condamine Road enters from the west.

The Condamine River passes to the west of the town.

The Roma to Brisbane Pipeline passes to the south of Condamine. There are two gas compression facilities to the east of Condamine. This location is the intersection of the Roma to Brisbane pipeline, the Peat/Scotia Lateral and the Braemar Line Pack Pipeline.

Tieryboo Post Office opened on 21 May 1856. It was renamed Condamine in July of that year.

Condamine State School opened on 1 January 1863.