Cúcuta Deportivo Fútbol Club S. A. (Spanish pronounced [ˈkukuta ðepoɾˈtiβo fuðˈbol ˈkluβ]), commonly referred to as Cúcuta Deportivo, is a professional Colombian football club from the city of Cúcuta. Founded on 10 September 1924, it is one of the oldest active football clubs in the country; specifically the fourth oldest club. Since the 1950 season, it has taken part in the Colombian professional football league, year in which it joined professionalism, and since that season it has played its home games at the Estadio General Santander, with a capacity for 42,000 spectators. It currently plays in Categoría Primera B, the second level of the Colombian football league system.

Identified by its red and black colors – by which they are known as the rojinegros, Cúcuta Deportivo is one of Colombia's historical clubs. The club won its first Primera A championship in the 2006–II season. It also has three Second Division titles, won in the 1995–96, 2005 and 2018 seasons. It participated in the 2007 Copa Libertadores, achieving an outstanding continental performance by reaching the semi-finals, stage in which it faced Boca Juniors, eventual champions of the tournament; and in the 2008 Copa Libertadores, achieving another good participation, in which it reached the round of 16, stage in which it lost to Brazilian side Santos.

In 2012, the IFFHS published a ranking of clubs in South America with statistical data from 2001 to 2012, in which Cúcuta was highlighted as one of the best Colombian teams, ranked 92nd at continental level in the 21st century. It also ranks 146th in the all-time club world rankings according to the IFFHS, being the fifth best placed Colombian team on the list.

Its classic rival is Atlético Bucaramanga, against which it plays in the Clásico del Oriente Colombiano in which it leads the all-time series of clashes. Cúcuta has one of the largest fanbases in the country.

There is some dispute regarding the founding year of Cúcuta Deportivo, but according to historian Alfredo Díaz, the club was founded on 10 September 1924 as Cúcuta Sports Club. The club's first games outside of Colombia were against a team composed of players representing Caracas, Venezuela on 23 November 1926. Two days later, on 25 November, the team played in La Guaira, Venezuela. Cúcuta Sports Club became the base of the Norte de Santander football team that took part in the first Colombian National Games (Juegos Deportivos Nacionales de Colombia) in 1928 in the city of Cali.

On 15 May 1949, the president of the Colombian football league invited the directors of Club Colpet, Chinaquillo, Guasimales, and Unión Frontera to strengthen Cúcuta Deportivo to compete in the new Colombian professional football league. To facilitate the economic reforms required to join the league, Hernando Lara Hernández bought 1,700 shares in the club in September of the same year.

Between September and November 1949, before beginning its first campaign in the Colombian league, Cúcuta played Huracán de Medellín, Universidad de Bogotá, Boca Juniors de Cali, and Atlético Bucaramanga. The latter of these, Atlético Bucaramanga, is Cúcuta's arch rival, and their games are called the clásico of Eastern Colombia.

In 1950, Cúcuta played in the professional league with a team consisting of 12 Uruguayan players.