Dickinson College is a private liberal arts college in Carlisle, Pennsylvania, United States. Founded in 1773 as Carlisle Grammar School, Dickinson was chartered on September 9, 1783, making it the first college to be founded after the formation of the United States. Dickinson was founded by Benjamin Rush, a Founding Father and signer of the Declaration of Independence. The college is named in honor of John Dickinson, a Founding Father who voted to ratify the Constitution and later served as governor of Pennsylvania, and his wife Mary Norris Dickinson, who donated much of their extensive personal libraries to the new college.

The Carlisle Grammar School was founded in 1773 as a frontier Latin school for young men in Western Pennsylvania. Within years Carlisle's elite, such as James Wilson and John Montgomery, were pushing for the development of the school as a college. In 1782, Benjamin Rush, a physician who was a prominent leader during and after the American Revolution, met in Philadelphia with Montgomery and William Bingham, a prominent businessman and politician. As their conversation about founding a frontier college in Carlisle took place on his porch, "Bingham's Porch" was long a rallying cry at Dickinson.

Dickinson College was chartered by the Pennsylvania legislature on September 9, 1783; it was the first college to be founded in the newly independent United States of America. Rush intended to name the college after the president of Pennsylvania John Dickinson and his wife Mary Norris Dickinson, proposing "John and Mary's College." The Dickinsons had given the new college an extensive library which they jointly owned, one of the largest libraries in the colonies. The name Dickinson College was chosen instead. Dickinson College's location west of the Susquehanna River made it the westernmost college in the United States at the time of its 1783 founding. Rush made his first journey to Carlisle to attend the first meeting of the trustees, held in April 1784. The trustees selected Charles Nisbet, a Scottish minister and scholar, to serve as the college's first president. He arrived and began to serve on July 4, 1785, serving until his unexpected death in 1804.

Among Dickinson's 18th century graduates were Robert Cooper Grier and Roger Brooke Taney, both of whom later became U.S. Supreme Court justices.

A combination of financial troubles and faculty dissension led to a college closing from 1816 to 1821. In 1832, when the trustees were unable to resolve a faculty curriculum dispute, they ordered Dickinson's temporary closure a second time.

The law school was founded in 1834, the third school of law established in the United States. It became a separate school in 1890, although the law school and college continued to share a president until 1912. The law school is now affiliated with the Penn State University.

During the 19th century, two noted Dickinson College alumni had prominent roles in the lead-up to the Civil War. They were James Buchanan, the fifteenth president of the United States, and Roger Brooke Taney, the fifth chief justice of the United States. Dickinson is one of three liberal arts colleges to have graduated a president and a chief justice (Bowdoin and Amherst are the others). Taney led the Supreme Court in its ruling on the Dred Scott v. Sandford decision, which held that Congress could not prohibit slavery in federal territories, overturning the Missouri Compromise. Buchanan threw the full prestige of his administration behind congressional approval of the Lecompton Constitution in Kansas. During the Civil War, the campus and town of Carlisle were occupied twice by Confederate forces in 1863.

Carlisle was also the location of the Carlisle Barracks, which was converted in the late 1870s for use as the Carlisle Indian Industrial School. In 1879, Dickinson College and the nearby Carlisle Indian School began a collaboration, when James Andrew McCauley, president of the college, led the first worship service at the Indian School. The collaboration between the institutions lasted almost four decades, from the opening day to the closing of the Indian School in 1918. Dickinson College professors served as chaplains and special faculty to the Native American students. Dickinson College students volunteered services, observed teaching methods, and participated in events at the Indian School. Dickinson College accepted select Indian School students to attend its Preparatory School ("Conway Hall") and gain college-level education.