BBB National Programs, an independent non-profit organization that oversees more than a dozen national industry self-regulation programs that provide third-party accountability and dispute resolution services to companies, including outside and in-house counsel, consumers, and others in arenas such as privacy, advertising, data collection, child-directed marketing, and more. The Center for Industry Self-Regulation (CISR) is BBB National Programs' 501(c)(3) non-profit foundation. CISR supports responsible business leaders in developing fair, future-proof best practices, and the education of the public on the conditions necessary for industry self-regulation.

The self-regulatory system includes the following investigative, enforcement, and appellate units:

Parties may appeal decisions reached by NAD and CARU to NARB, the appellate body. Decisions reached by the self-regulatory system's investigative and appellate units are publicly reported through a press release.^{[citation needed]} In addition, the decisions reported by NAD and CARU also are compiled 10 times each year into the “NAD/CARU Case Reports.” As of 2010, more than 5,000 self-regulatory decisions are included in the NARC Online Archive. The case reports and archive are not public, however; access to the archive is $6900.00 a year, even though procedures state that final case decisions are public.

The National Advertising Division (NAD), established in 1971, is charged with monitoring and evaluating truth and accuracy in national advertising. The NAD examines and evaluates a wide range of advertising claims, including puffery, consumer surveys, product testing and product demonstrations, taste tests, pricing claims and disclosures. Through its unique window on the marketplace, NAD identifies hot issues in advertising and promotion. NAD's decisions assist advertisers in anticipating and responding to the challenges that new products and new media can pose.

Since its inception, NAD has examined advertising claims for a wide range of products, including:

In cooperation with the Council for Responsible Nutrition, NAD expanded its review of advertising for dietary supplements, a nearly $25 billion industry that is frequently criticized for misleading advertising. The program closed more than 360 cases concerning claims made in dietary supplement advertising. The program ended on July 1, 2020. The NAD opens hundreds of cases each year and more than 95 percent of the advertisers that appear before NAD voluntarily comply with NAD's decisions.

NAD cases often originate through a challenge filed by one advertiser against the advertising claims made by a competing advertiser. In addition, NAD monitors national advertising and investigates complaints filed by consumers and advocacy groups or referred by local Better Business Bureaus. The course of NAD review proceedings is detailed in The Advertising Industry's Process of Self-Regulation, Policies and Procedures by the National Advertising Review Council. The Procedures describe and explain the filing deadlines and requirements for submissions from challengers and advertisers. NAD examines advertising to determine whether the evidence provided by the advertiser fully supports the advertising claims at issue in an NAD review.

The NAD can be expected to make one of three determinations for every claim at issue.