Ernestine Rose died in Brighton, England, at the age of 82. She was buried at Highgate Cemetery in London. This date marks the end of a life dedicated to advocating for women's rights, abolition, and freethought.

Ernestine Rose and her husband, William Ella Rose, set sail for England from the United States due to her declining health. A farewell party was organized by Susan B. Anthony, and they received gifts and money from friends and admirers.