Mean sea level (MSL, often shortened to sea level) is an average surface level of one or more among Earth's coastal bodies of water from which heights such as elevation may be measured. The global MSL is a type of vertical datum – a standardised geodetic datum – that is used, for example, as a chart datum in cartography and marine navigation, or, in aviation, as the standard sea level at which atmospheric pressure is measured to calibrate altitude and, consequently, aircraft flight levels. A common and relatively straightforward mean sea-level standard is instead a long-term average of tide gauge readings at a particular reference location.

The term above sea level generally refers to the height above mean sea level (AMSL). The term APSL means above present sea level, comparing sea levels in the past with the level today.

Earth's radius at sea level is 6,378.137 km (3,963.191 mi) at the equator. It is 6,356.752 km (3,949.903 mi) at the poles and 6,371.001 km (3,958.756 mi) on average. This flattened spheroid, combined with local gravity anomalies, defines the geoid of the Earth, which approximates the local mean sea level for locations in the open ocean. The geoid includes a significant depression in the Indian Ocean, whose surface dips as much as 106 m (348 ft) below the global mean sea level (excluding minor effects such as tides and currents).

Precise determination of a "mean sea level" is difficult because of the many factors that affect sea level. Instantaneous sea level varies substantially on several scales of time and space. This is because the sea is in constant motion, affected by the tides, tsunamis, wind, atmospheric pressure, local gravitational differences, temperature, salinity, and so forth. The mean sea level at a particular location may be calculated over an extended time period and used as a datum. For example, hourly measurements may be averaged over a full Metonic 19-year lunar cycle to determine the mean sea level at an official tide gauge.

Still-water level or still-water sea level (SWL) is the level of the sea with motions such as wind waves averaged out. Then MSL implies the SWL further averaged over a period of time such that changes due to, e.g., the tides, also have zero mean. Global MSL refers to a spatial average over the entire ocean area, typically using large sets of tide gauges and/or satellite measurements.

One often measures the values of MSL with respect to the land; hence a change in relative MSL or (relative sea level) can result from a real change in sea level, or from a change in the height of the land on which the tide gauge operates, or both. In the UK, the ordnance datum (the 0 metres height on UK maps) is the mean sea level measured at Newlyn in Cornwall between 1915 and 1921. Before 1921, the vertical datum was MSL at the Victoria Dock, Liverpool. Since the times of the Russian Empire, in Russia and its other former parts, now independent states, the sea level is measured from the zero level of Kronstadt Sea-Gauge. In Hong Kong, "mPD" is a surveying term meaning "metres above Principal Datum" and refers to height of 0.146 m (5.7 in) above chart datum and 1.304 m (4 ft 3.3 in) below the average sea level. In France, the Marégraphe in Marseille measures continuously the sea level since 1883 and offers the longest collated data about the sea level. It is used for a part of continental Europe and the main part of Africa as the official sea level. Spain uses the reference to measure heights below or above sea level at Alicante, while the European Vertical Reference System is calibrated to the Amsterdam Peil elevation, which dates back to the 1690s.

Satellite altimeters have been making precise measurements of sea level since the launch of TOPEX/Poseidon in 1992. A joint mission of NASA and CNES, TOPEX/Poseidon was followed by Jason-1 in 2001 and the Ocean Surface Topography Mission on the Jason-2 satellite in 2008.

Height above mean sea level (AMSL) is the elevation (on the ground) or altitude (in the air) of an object, relative to a reference datum for mean sea level (MSL). It is also used in aviation, where some heights are recorded and reported with respect to mean sea level (contrast with flight level), and in the atmospheric sciences, and in land surveying. An alternative is to base height measurements on a reference ellipsoid approximating the entire Earth, which is what systems such as GPS do. In aviation, the reference ellipsoid known as WGS84 is increasingly used to define heights; however, differences up to 100 metres (328 feet) exist between this ellipsoid height and local mean sea level. Another alternative is to use a geoid-based vertical datum such as NAVD88 and the global EGM96 (part of WGS84). Details vary in different countries.