Frizzled-2 (Fz-2) is a protein that in humans is encoded by the FZD2 gene.

Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The expression of the FZD2 gene appears to be developmentally regulated, with high levels of expression in fetal kidney and lung and in adult colon and ovary.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.