Fábio Mello (born June 28, 1975) is a Brazilian mixed martial artist who fought on Pride Fighting Championships, DEEP, Shooto, Bellator Fighting Championships, Jungle Fight and Titan Fighting Championships. He is currently the no gi and brazilian jiu-jitsu trainer of Imperial Athletics.

Mello started his career in 2001. Between 2001 and 2008, he fought only for Japanese and Brazilian promotions like Pride Fighting Championships, DEEP, Jungle Fight and Meca World Vale Tudo. He compiled a record of four wins and six losses, facing opponents like Takanori Gomi, José Aldo and Fredson Paixão.

Mello faced Sami Aziz on June 19, 2009, at Bellator 12. He defeated Aziz via submission due to an armbar in the third round.

On November 19, 2011, at Bellator 58, Mello faced Farkhad Sharipov. He won via unanimous decision after three rounds (30-27, 30–27, 30–27).

Mello faced Josh Huber on March 2, 2012, at Titan Fighting Championships 21. He defeated Huber via submission in the first round.

Mello was expected to face Nick Mamalis on May 25, 2012, at Titan Fighting Championships 22. But for undisclosed reasons, Mamalis was replaced by Angelo Duarte. Once again Mello won via submission in the first round.

Mello was expected to face Waylon Lowe on November 3, 2012, at WSOF 1. However, the fight was scrapped due to Mello getting injured.

Mello made his debut against Nick LoBosco on October 26, 2013, at WSOF 6. He lost via knockout in the first round.