Ferredoxin—NAD(+) reductase
Ferredoxin—NAD(+) reductase
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Ferredoxin—NAD(+) reductase

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Ferredoxin—NAD(+) reductase

In enzymology, a ferredoxin–NAD+ reductase (EC 1.18.1.3) is an enzyme that catalyzes the chemical reaction:

Thus, the two substrates of this enzyme are reduced ferredoxin and NAD+, whereas its 3 products are oxidized ferredoxin, NADH, and H+. This enzyme participates in fatty acid metabolism.

This enzyme belongs to the family of oxidoreductases, specifically those acting on iron-sulfur proteins as donor with NAD+ or NADP+ as acceptor.

The systematic name of this enzyme is ferredoxin:NAD+ oxidoreductase. There are a variety of names in common use:

When NAD molecule is in its reduced form, the enzyme is referred to as:

Other enzymes in the family include:

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code PDB: 1KRH​.

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