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GPR89B

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GPR89B

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GPR89B

GPR89B

Identifiers

GPR89B, GPHR, GPR89, GPR89C, SH120, UNQ192, G protein-coupled receptor 89B

External IDs

OMIM: 612806; MGI: 1914799; HomoloGene: 9475; GeneCards: GPR89B; OMA:GPR89B - orthologs

Gene location (Human)

Chr.	Chromosome 1 (human)^[1]

Band	1q21.2	Start	147,928,393 bp^[1]
Band	1q21.2	End	147,993,592 bp^[1]

Gene location (Mouse)

Chr.	Chromosome 3 (mouse)^[2]

Band	3\|3 F2.1	Start	96,775,597 bp^[2]
Band	3\|3 F2.1	End	96,812,662 bp^[2]

RNA expression pattern

Human

Mouse (ortholog)

Top expressed in

testicle

duodenum

corpus callosum

Achilles tendon

human kidney

body of pancreas

granulocyte

cerebellar cortex

cerebellar hemisphere

right lobe of liver

Top expressed in

spermatocyte

lacrimal gland

jejunum

otic vesicle

ileum

saccule

intestinal epithelium

interventricular septum

epithelium of small intestine

right lobe of liver

More reference expression data

n/a

Gene ontology
Molecular function	voltage-gated anion channel activity signal transducer activity voltage-gated ion channel activity
Cellular component	integral component of membrane Golgi cisterna membrane Golgi-associated vesicle membrane Golgi membrane Golgi apparatus membrane
Biological process	protein transport positive regulation of I-kappaB kinase/NF-kappaB signaling regulation of ion transmembrane transport ion transport intracellular pH reduction signal transduction regulation of anion transmembrane transport transport ion transmembrane transport inorganic anion transport
Sources:Amigo / QuickGO

Species

Human

Mouse


51463


67549


ENSG00000188092


ENSMUSG00000028096


P0CG08


Q8BS95

RefSeq (mRNA)

NM_001097616 NM_001350180 NM_001350181 NM_001350182 NM_001350183
NM_001350184 NM_016334


NM_026229

RefSeq (protein)

NP_001091081 NP_001091082 NP_001337109 NP_001337110 NP_001337111
NP_001337112 NP_001337113 NP_057418 NP_001337109 NP_001337110 NP_001337111 NP_001337112 NP_001337113 NP_057418 NP_001091081 NP_001091082


NP_080505

Location (UCSC)

Chr 1: 147.93 – 147.99 Mb

Chr 3: 96.78 – 96.81 Mb

PubMed search

^[3]

^[4]

View/Edit Human

View/Edit Mouse

Protein GPR89 is a protein that in humans is encoded by the GPR89B gene.^[5]^[6]

Related gene problems

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000188092 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000028096 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Zhang QH, Ye M, Wu XY, Ren SX, Zhao M, Zhao CJ, Fu G, Shen Y, Fan HY, Lu G, Zhong M, Xu XR, Han ZG, Zhang JW, Tao J, Huang QH, Zhou J, Hu GX, Gu J, Chen SJ, Chen Z (Nov 2000). "Cloning and Functional Analysis of cDNAs with Open Reading Frames for 300 Previously Undefined Genes Expressed in CD34+ Hematopoietic Stem/Progenitor Cells". Genome Res. 10 (10): 1546–60. doi:10.1101/gr.140200. PMC 310934. PMID 11042152.
^ "Entrez Gene: GPR89A G protein-coupled receptor 89A".

Further reading

Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Lai CH, Chou CY, Ch'ang LY, et al. (2000). "Identification of Novel Human Genes Evolutionarily Conserved in Caenorhabditis elegans by Comparative Proteomics". Genome Res. 10 (5): 703–13. doi:10.1101/gr.10.5.703. PMC 310876. PMID 10810093.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Matsuda A, Suzuki Y, Honda G, et al. (2003). "Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways". Oncogene. 22 (21): 3307–18. doi:10.1038/sj.onc.1206406. PMID 12761501.
Clark HF, Gurney AL, Abaya E, et al. (2003). "The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi:10.1038/nature04727. PMID 16710414.

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