Gattuso began his managerial career with Palermo.

Gattuso managed OFI Crete in Greece.

Gattuso led Pisa to Serie B promotion.

Gattuso managed AC Milan's youth team and later the first team.

Gattuso won the Coppa Italia with Napoli in the 2019-20 season.

Gattuso managed Valencia CF in La Liga.

Gattuso had a brief stint at Olympique Marseille.

Gattuso is currently managing Hajduk Split in the Croatian Football League.