Main campus of the Georgia Institute of Technology

The main campus of the Georgia Institute of Technology occupies part of Midtown Atlanta, primarily bordered by 10th Street to the north, North Avenue to the south, and, with the exception of Tech Square, the Downtown Connector to the East, placing it well in sight of the Atlanta skyline. In 1996, the campus was the site of the athletes' village and a venue for a number of athletic events for the 1996 Summer Olympics. The construction of the Olympic Village, along with subsequent gentrification of the surrounding areas, significantly changed the campus.

The Georgia Tech campus is located in Midtown, an area north of downtown Atlanta. Although a number of skyscrapers (most visibly AT&T Midtown Center, One Coca-Cola Plaza, and Bank of America Plaza) are visible from all points on campus, the campus itself has few buildings over four stories and has a great deal of greenery. This gives it a distinctly suburban atmosphere quite different from other Atlanta campuses such as that of Georgia State University.

In addition to the main campus, Georgia Tech also operates satellite campuses in Savannah, Georgia (Georgia Tech Savannah); Metz, France (Georgia Tech Lorraine); Athlone, Ireland; Shenzhen, China; and Singapore.

The campus is organized into four main parts: West Campus, East Campus, Central Campus, and Technology Square. West Campus and East Campus are both occupied primarily by student living complexes, while Central Campus is reserved primarily for teaching and research buildings.

Formerly the location of the Hemphill Avenue neighborhood, Georgia Tech began to expand into this area in 1965. West Campus is occupied primarily by apartments and coed undergraduate dormitories. Apartments include Crecine, Center Street, Zbar, Maulding, Nelson-Shell, and Eighth Street Apartments (all of which were built as part of the 1996 Olympic Village), while dorms include Freeman, Montag, Fitten, Folk, Caldwell, Armstrong, Hefner, Fulmer, and Woodruff Suites. The Campus Recreation Center (formerly the Student Athletic Complex); a volleyball court; a large, low natural green area known as the Burger Bowl; and a flat artificial green area known as the Stamps Field (formerly SAC Field) are all located on the western side of the campus.

West Campus was formerly home to Under the Couch, which relocated to the Student Center in the fall of 2010. Also within walking distance of West Campus are several late-night eateries, primarily on Northside Drive. Engineer's Bookstore, an economical alternative to Georgia Tech's official bookstore, also operated near West Campus until its closure in 2016. West campus was home to a convenience store, West Side Market, which closed in 2017. Due to limited space, all auto travel proceeds via a network of one-way streets which connects West Campus to Hemphill Avenue and Ferst Drive, the main road of the campus. Woodruff Dining Hall, or "Woody's", was the West Campus Dining Hall before its closure in 2017. It connected the Woodruff North and Woodruff South undergraduate dorms. In 2017, West Village, a multipurpose facility featuring dining options, meeting space, School of Music classrooms, and offices to West Campus, opened.

East Campus houses all of the fraternities and sororities as well as most of the undergraduate freshman dormitories. East Campus abuts the Downtown Connector, granting residences quick access to Midtown and its businesses (for example, The Varsity) via several bridges over the highway, as well as a tunnel beneath it. Georgia Tech football's home, Bobby Dodd Stadium is located on East Campus, as well as Georgia Tech basketball's home, McCamish Pavilion (formerly Alexander Memorial Coliseum).

Brittain Dining Hall is the main dining hall for East Campus. It is modeled after a medieval church, complete with carved columns and stained glass windows showing symbolic figures. The main road leading from East Campus to Central Campus is a steep ascending incline commonly known as "Freshman Hill" (in reference to the large number of freshman dorms near its foot). On March 8, 2007, the former Georgia State University Village apartments were transferred to Georgia Tech. Renamed North Avenue Apartments by the institute, they began housing students in the fall semester of 2007.