HSBC Main Building is a headquarters building of The Hongkong and Shanghai Banking Corporation, which is today a wholly owned subsidiary of London-based HSBC Holdings. It is located on the southern side of Statue Square near the location of the old City Hall, Hong Kong (built in 1869, demolished in 1933). The previous HSBC building was built in 1935 and pulled down to make way for the current building. The address remains as 1 Queen's Road Central (the north facing side of the building was served by Des Voeux Road Central, which was the seashore, making Queen's Road the main entrance, in contrast to the current primary access coming from Des Voeux Road).

The first HSBC (then known as the Hong Kong and Shanghai Banking Company Limited) building was Wardley House, used as an HSBC office between 1865 and 1882 on the present site. In 1864 the lease cost HKD 500 a month. After raising a capital of HKD 5 million, the bank opened its doors in 1865.

Wardley House was subsequently demolished and replaced by a second HSBC building that was completed in 1886. The main feature of the second building design was the division of the structure into two almost separate buildings. The building on Queen's Road Central was in Victorian style with a verandah, colonnades and an octagonal dome, whereas an arcade which harmonised with the adjacent buildings was constructed on Des Voeux Road. It was designed by Clement Palmer in 1883.

In 1934, the second building was demolished and a third design was erected. The new building opened in October 1935. Upon completion, the building stood as the tallest building in Hong Kong and "the largest building in the Far East", "the tallest structure in South East Asia", and "tallest building between Cairo and San Francisco". The third design used part of the land of the old City Hall, and was built in a mixed Art Deco and Stripped Classical style. During the Japanese occupation of Hong Kong between 1941 and 1945, the building served as the government headquarters. It was the first building in Asia to be fully air-conditioned. By the 1970s, the bank had outgrown its headquarters; departments were scattered into offices all over Central, and it was obvious that such a "solution" to the space limitations could not continue indefinitely. In 1978, the bank decided to replace it with a new building intended to symbolize the bank’s modernization and the city’s increasing prominence in global finance. Construction began in 1981 and concluded in 1985.

The current building is a steel suspended structure designed by Norman Foster, was completed on 18 November 1985. The building was officially opened on 7 April 1986. At the time, it was the most expensive building in the world (c.a. HK$5.2 billion, roughly US$668 million). The decision to replace the previous headquarters marked the bank's goals for modernization and role in growth as a financial center.

The first major addition to the building, designed by Hong Kong's One Space Ltd, was completed on 23 November 2006, in the form of a ground floor lobby that improves security access to the upper floors and creates a prestigious reception area. Its design and construction included the installation of the "Asian Story Wall", a multimedia installation consisting of twin banks of 30 seamless plasma screens (the largest installation of its kind in Hong Kong) displaying archived bank heritage and artworks.

The atrium of the HSBC building was the site of the Occupy Hong Kong protests which maintained a presence in the building from 15 October 2011 until their eviction in September 2012.

The new building was designed by the British architect Norman Foster (Foster Associates) and civil & structural engineers Ove Arup & Partners with service design by J. Roger Preston & Partners. It was constructed by the John Lok / Wimpey Joint Venture. From the concept to completion, it took seven years (1978–1985). The building is 180 metres high with 47 storeys and four basement levels. The building has a modular design consisting of five steel modules, which were prefabricated in the UK by Scott Lithgow Shipbuilders near Glasgow and shipped to Hong Kong. About 30,000 tons of steel and 4,500 tons of aluminium were used.