Hanceville is a city in Cullman County, Alabama, United States. At the 2020 census, the population was 3,217.

Founded in Blount County, Hanceville was established in 1832 and incorporated in May 1879. At the time of Cullman County's creation in 1877, half of Hanceville resided in each county. In 1885, county boundaries were redrawn and all of Hanceville was placed within Blount County. In 1901, county boundaries were redrawn again and this time all of the town was placed within Cullman County, in which it has remained.

Hanceville is located in southeastern Cullman County. U.S. Route 31 passes through the city, leading north 9 miles (14 km) to Cullman, the county seat, and south 14 miles (23 km) to Smoke Rise.

According to the U.S. Census Bureau, the city has a total area of 4.2 square miles (10.9 km²), of which 0.02 square miles (0.04 km²), or 0.34%, is water.

As of the 2020 census, Hanceville had 3,217 people, 1,263 households, and 730 families. The population density was 789 inhabitants per square mile (305/km²). The median age was 42.3 years. 17.3% of residents were under the age of 18 and 23.7% of residents were 65 years of age or older. For every 100 females there were 82.8 males, and for every 100 females age 18 and over there were 78.6 males age 18 and over.

0.0% of residents lived in urban areas, while 100.0% lived in rural areas.

There were 1,263 households in Hanceville, of which 25.0% had children under the age of 18 living in them. Of all households, 35.6% were married-couple households, 20.9% were households with a male householder and no spouse or partner present, and 36.9% were households with a female householder and no spouse or partner present. About 35.3% of all households were made up of individuals and 16.7% had someone living alone who was 65 years of age or older.

There were 1,451 housing units, of which 13.0% were vacant. The homeowner vacancy rate was 4.2% and the rental vacancy rate was 12.3%.