Hayat Sindi was born in Mecca, Saudi Arabia. Her upbringing fostered a curiosity and passion for science, laying the foundation for her future endeavors. This marked the beginning of a life dedicated to challenging societal norms and pursuing scientific excellence.

Defying societal expectations in Saudi Arabia at the time, Sindi convinced her family to allow her to pursue higher education abroad. She moved to the United Kingdom to study at Girton College, Cambridge University. This period demonstrates her determination to pursue her intellectual curiosity and gain access to world-class education, a defining characteristic of her career.