Henrietta Vansittart died of acute mania and anthrax at St Nicholas's Hospital in Gosforth. Her death marked the end of a pioneering career in engineering and invention, despite facing societal limitations as a woman in the 19th century.

Henrietta Vansittart was admitted to St Nicholas's Hospital, Gosforth, after being found confused and exhibiting signs of mania. This event marked the beginning of her final months and the decline of her mental and physical health.