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IGHG4

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IGHG4

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IGHG4

IGHG4

Identifiers

IGHG4, immunoglobulin heavy constant gamma 4 (G4m marker)

External IDs

OMIM: 147130; GeneCards: IGHG4; OMA:IGHG4 - orthologs

Gene location (Human)

Chr.	Chromosome 14 (human)^[1]

Band	14q32.33	Start	105,620,506 bp^[1]
Band	14q32.33	End	105,626,066 bp^[1]

RNA expression pattern

Human

Mouse (ortholog)

Top expressed in

appendix

duodenum

spleen

gallbladder

bone marrow cell

mucosa of transverse colon

lymph node

rectum

right lobe of liver

right coronary artery

n/a

More reference expression data

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Species

Human

Mouse


3503


n/a


ENSG00000211892


n/a


n a


n/a

RefSeq (mRNA)


n/a


n/a

RefSeq (protein)


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n/a

Location (UCSC)

Chr 14: 105.62 – 105.63 Mb

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PubMed search

^[2]

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View/Edit Human

Ig gamma-4 chain C region is a protein that in humans is encoded by the IGHG4 gene.^[3]

See also

Immunoglobulin heavy chain (IGH)
Immunoglobulin G (IgG)
- Subclasses of IgG, IgG4 is encoded by this gene
IgG4-related disease

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000211892 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: IGHG4 immunoglobulin heavy constant gamma 4 (G4m marker)".

Further reading

McLean GR, Nakouzi A, Casadevall A, Green NS (Oct 2000). "Human and murine immunoglobulin expression vector cassettes". Molecular Immunology. 37 (14): 837–45. doi:10.1016/S0161-5890(00)00101-2. PMID 11257305.
Ellison J, Hood L (Mar 1982). "Linkage and sequence homology of two human immunoglobulin gamma heavy chain constant region genes" (PDF). Proceedings of the National Academy of Sciences of the United States of America. 79 (6): 1984–8. Bibcode:1982PNAS...79.1984E. doi:10.1073/pnas.79.6.1984. PMC 346106. PMID 6804948.
Flanagan JG, Lefranc MP, Rabbitts TH (Mar 1984). "Mechanisms of divergence and convergence of the human immunoglobulin alpha 1 and alpha 2 constant region gene sequences". Cell. 36 (3): 681–8. doi:10.1016/0092-8674(84)90348-9. PMID 6421489. S2CID 54312675.
Hisajima H, Nishida Y, Nakai S, Takahashi N, Ueda S, Honjo T (May 1983). "Structure of the human immunoglobulin C epsilon 2 gene, a truncated pseudogene: implications for its evolutionary origin". Proceedings of the National Academy of Sciences of the United States of America. 80 (10): 2995–9. doi:10.1073/pnas.80.10.2995. PMC 393960. PMID 6407005.
Ueda S, Nakai S, Nishida Y, Hisajima H, Honjo T (1984). "Long terminal repeat-like elements flank a human immunoglobulin epsilon pseudogene that lacks introns". The EMBO Journal. 1 (12): 1539–44. doi:10.1002/j.1460-2075.1982.tb01352.x. PMC 553248. PMID 6327276.
Ellison J, Buxbaum J, Hood L (1983). "Nucleotide sequence of a human immunoglobulin C gamma 4 gene". DNA. 1 (1): 11–8. doi:10.1089/dna.1.1981.1.11. PMID 6299662.
Pink JR, Buttery SH, De Vries GM, Milstein C (Mar 1970). "Human immunoglobulin subclasses. Partial amino acid sequence of the constant region of a gamma 4 chain". The Biochemical Journal. 117 (1): 33–47. doi:10.1042/bj1170033. PMC 1178827. PMID 4192699.

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