Hotel Babylon is a British television drama series based on the 2004 book of the same name by Imogen Edwards-Jones, that aired from 19 January 2006 to 14 August 2009, produced by independent production company Carnival Films for BBC One. The show followed the lives of workers at a glamorous five-star hotel.

The show was cancelled after its fourth series, leaving the series 4 finale cliffhanger unresolved.

Sam Franklin arrives at the beginning of the fourth series, when London is brought to a halt by terrorist alarms. He becomes involved in affairs when he encourages the staff to open the hotel to as many people as possible, and it is revealed that he is the ex-husband of Juliet, who is overseeing the closure of the hotel. The charismatic, attractive businessman was previously unsuccessful but due to investments in a Chinese wind farm has now become a multi-millionaire. When a potential deal falls through, he steps in and buys the hotel himself, saving it from closure.

When he loses everything except the hotel, he becomes heavily involved in management, leading to tensions between himself and his ex-wife. Despite their divorce, they decide to celebrate their wedding anniversary and thereafter renew their sexual relationship. However, when he discovers that she had had an abortion when he left, they break up, and he begins to fall for Emily, the PR manager.

Juliet Miller (previously Franklin) arrived originally as a bailiff when the hotel was facing closure in the opener of series four, but took the job of general manager when ex-husband Sam bought Babylon. She is described as professional and first rate at her job, Juliet takes no prisoners and has no room for sentiment when livelihoods and millions of pounds are at stake. Juliet has no issue making tough decisions but when it comes to her personal life she is thrown off course when former husband Sam turns up at the hotel. However, the two decided to work together and became friendly together. However, in episode 5, a brief incident involving Meredith Sutton made a rupture in the relationship. Meredith Sutton was a consultant who Sam hired to build the hotel's management team. However, Meredith was actually Sam's girlfriend and Juliet grew jealous and briefly left Hotel Babylon. Meredith Sutton opted for the job and Sam agreed until he found out a minute later that she had tampered with the exercise. Sam went after Juliet and managed to get her to return.

Tony Casemore is played by actor Dexter Fletcher. He first appeared in Series 1, Episode 1. Emily James stated that Casemore knows London inside out. The character is currently the head concierge but his previous role was Deputy Manager. Casemore is married and has two children; his daughter appears in Series 3. It is revealed in Series 3 that his family are often irritated at him for being at work a lot of the time. Casemore takes his work very seriously and gets annoyed when Rebecca Mitchell says the word concierge sounds "seedy". He uses his knowledge of London to help the guests anyway he can, in some cases this includes finding prostitutes. Casemore has a good friendship with his fellow workers at the hotel, in particular Anna; their relationship could be described as paternal as well as good friends.

Dexter Fletcher said on his character, "Yes he is a good family man and he always tries to make the right decision. The writers are really challenging Tony's values this series." "He sacrifices a lot in order to create a comfortable family life at home for his wife and children, and there is always that unintentional clash because he does work so hard he never gets to see his family." "When his daughter Liz turns up at the hotel for an audition a lot of home truths hit him and he is forced to reassess his position both as a father and within the hotel."

Gino Primirola is played by actor Martin Marquez. He first appeared in the series in Series 1, Episode 1. Gino has worked at the bar in the hotel for many years. A native of Rome, Italy, he grew up in Spain and still has a strong Spanish accent.