The universe of the manga and anime series Bobobo-bo Bo-bobo is a home to a wide array of fictional characters. This article will lay out all the characters contained in this universe, and categorize them into the type of character they are in the series.

Voiced by: Takehito Koyasu (Japanese); Richard Epcar (English)

Bobobo-bo Bo-bobo (ボボボーボ・ボーボボ, Bobobōbo Bōbobo) is the main protagonist and title character. Bo-bobo is an eccentric man with bodybuilder sized muscles and a giant, yellow, spherical afro. He fights the forces of evil using his nose hair calling it his "Fist of the Nose Hair" and "Snot Fo-You" technique. He is 27 years old, although his birthday differs between the manga and the anime.

Voiced by: Ai Nonaka (Japanese); Philece Sampler (English)

Beauty (ビュティ, Byuti) is the female heroine of Bo-bobo's group and usually the only girl when Torpedo Girl or Suzu are not around. A stereotypical teenage manga heroine, she is one of the few sane characters who is the first to join Bo-bobo and was the only citizen to still have hair after the attack of the town she lived in. She initially wanted to join Bo-bobo because she sought a life of adventure. Bo-bobo let her join him, but rejected Pickles, stating that he didn't like him, at the same time. She has loving feelings for Gasser after he rescued her, but doesn't say anything about them. She is often exasperated by Bo-bobo's odd behavior or the behavior or actions of others, usually with the same face. She's the only person in the group that doesn't fight, but still criticizes the others' fighting styles. There are a few rare occurrences where she was forced to fight to defend herself, but it's only when Bo-bobo isn't around to protect her and at the last minute someone would come and save her. Beauty worries about her friends' safety and finds them as her own family and though she finds Bo-bobo crazy, she idolizes him greatly. She seems to be a random girl who joins Bo-bobo's group unil Softon is "revealed" to be her brother, implying that she may have powers of her own or is descended from a powerful bloodline. By the end of the series, she is traveling the world with Heppokomaru/Gasser.

Voiced by: Masaya Onosaka (Japanese); Kirk Thornton (English)

Don Patch (首領パッチ, Don Patchi), Poppa Rocks in the English manga, is the original leader (or "don") of the "Wiggin Gang" ("Hajikegumi" in Japan), a group of rebels who oppose Czar Baldy Bald IV. Don Patch has henchmen named Lil' Rocks (in the English manga), or Ko Patch. He quits the Wiggin Gang claiming that they never gave him space, but really so he could wig out more with Bo-bobo. He is extremely narcissistic, and demands to be the center of attention; this leads him to hold a grudge against Beauty believing he should be the "heroine" of the show. Don Patch also has a wide variety of personas that he switches into, including a female one named "Patches."

Voiced by: Naomi Shindo (Japanese); Brad MacDonald (English)