Cuoco and Tom Pelphrey announced their engagement.

Cuoco gave birth to her daughter Matilda with partner Tom Pelphrey.

The Flight Attendant was renewed for a second season.

The Flight Attendant premiered on HBO Max, starring Cuoco as Cassie Bowden.

The DC Universe adult animation series Harley Quinn premiered, with Cuoco voicing the title character.

Cuoco married Karl Cook.

Cuoco became engaged to equestrian Karl Cook on her 32nd birthday.

Cuoco and Sweeting's divorce was finalized.

Cuoco married professional tennis player Ryan Sweeting in Santa Susana, California.

Cuoco broke her leg in a horse-riding accident and missed the filming of two episodes of The Big Bang Theory.

Cuoco starred in the Lifetime film To Be Fat like Me, which premiered on this date.

Kaley Christine Cuoco was born in Camarillo, California.