Kay-Anlog is a component barangay of the city in Calamba, Laguna, Philippines, situated in the southern part of the city, adjacent to the barangays of Milagrosa, Burol, Bubuyan, and Ulango.

Kay-Anlog is located at the southern edge of the city of Calamba, being one of the "upland barangays". At 272 hectares, it is one of the largest barangays by area in Calamba. It is a landlocked barangay bordered by Makiling and Milagrosa to the east, Ulango to the south, Punta to the north, Bubuyan and Burol to the west, Laurel, Batangas to the south. All of those districts are in Calamba, excluding barangay Laurel that is in Tanauan, Batangas.

Kay-Anlog is subdivided into 4 puroks (zones). These are:

Kay-Anlog has 6 subdivisions these are;

The namesake of the barangay is from Anlog, a man who is said to be the original resident of Buwisan and a former estate steward. He originally lived in Ulango, Tanauan, Batangas. The phrase "Kay Anlog" means "Anlog's property" as the area is named after him.

In the 1903 Philippine census, Buisan can be found as one of Calamba's barangays. It is said to be the former name of the barangay. In 1918 census, Quianlog appeared and Buisan disappeared from the census. This is due to changing of name of the barangay. Thru time, the barangay was eventually named Kay-Anlog.

In 1903 Census, the barangay was known as "Buisan". In 1918, it became "Quianlog" in 1948 it became "Buwisan" and on the following censuses it was named "Kay-Anlog".

Before 2010, Kay-Anlog was one of the barangays with the least population due to its remoteness especially from Calamba Poblacion. After the 2010 census, the population increased drastically due to government's housing projects in the barangay and became one of the most populous barangays in the city.