Knightley has been an ambassador for Oxfam, a global organization working to fight poverty. She has participated in various campaigns and initiatives to raise awareness and funds for Oxfam's work.

Knightley has been vocal about the pressure on women to conform to unrealistic beauty standards. She has spoken out against the use of airbrushing and the objectification of women in the media.

Knightley has been a supporter of the Time's Up movement, which aims to combat sexual harassment and inequality in the entertainment industry and beyond. She has attended events and spoken out in support of the movement's goals.

Knightley has supported organizations working to help refugees, highlighting the plight of displaced people around the world.