The King's School, Macclesfield, is an all through co-educational private day school in Prestbury, Cheshire, England, and a member of the Headmasters' and Headmistresses' Conference. It was founded in 1502 by Sir John Percyvale, a former Lord Mayor of London, as Macclesfield Grammar School.

The King's School was founded in 1502 within the Church of St Michael and All Angels, Macclesfield. It was re-founded by Edward VI in 1552 as the "Free Grammar School of King Edward VI". It moved to Cumberland Street, 300 metres further from the town square, in 1844. In July 2020, the school moved to a new location adjacent to its long-held Derby Playing Fields, on the outskirts of Macclesfield.

In 1844 a Modern School, with a more commercial and technical curriculum, was built by the governors to run in tandem with the Grammar School. It merged with the Grammar School in 1912.

The school operated as a direct-grant school and offered scholarships for boys from state elementary schools from 1926 until 1966, when its application to continue as a direct grant grammar school was refused and it became fully independent.

The boys' junior school was opened in 1947. In 1993, girls from age 11 to 16 were admitted and housed with co-educational juniors, and later infants, at the old Macclesfield High School site on Fence Avenue. The Sixth Form had been co-educational since 1986.

The King's School's 2020 development plans involved closing the two existing school sites in Macclesfield and opening a new single site school in Prestbury, near Macclesfield. The development plans involved selling off the two existing school sites for housing development to fund the new school site. The school acquired greenbelt farmland adjacent to its Derby Fields site for which it subsequently sought planning permission in order to develop the existing school site and the farmland for housing. Planning permission was granted to the school to build more than 250 houses on the greenbelt land in Macclesfield in July 2016. The new school was built on green belt land in nearby Prestbury. Planning permission for all sites was confirmed when the Secretary of State declined to call in the plans for further scrutiny in September 2016. In July 2020, King's School left Macclesfield after more than 500 years of continuous operation in the town and relocated to Prestbury. In 2024, after 500 years of teaching Latin, King’s school controversially withdrew Latin from its curriculum. This led to parents making a formal complaint to an independent body regarding this decision and the lack of transparent decision making by the school’s governing body.

The school follows the National Curriculum for GCSE in Years 10–11 and A-Levels in the sixth form. In 2012, pupils achieved A*/A in 41% of all exams and A* – B in three-quarters of exams. Pupils achieved the best-ever GCSE results in 2012 with 33% of grades at A* grade, more than 63% of grades at A*/A and 86% at A* – B grade.

In 2011, pupils achieved 75% A* to B grade at A-level, with a 99.7% pass rate, and 60% As and A*s at GCSE.