This is a list of soap opera characters who are lesbian, gay, bisexual, or transgender, and the live action television and radio soap operas which feature them. Characters who are pansexual, asexual, non-binary and intersex are also included. Character orientation and gender identity can be portrayed on-screen, described in the dialogue or mentioned. Characters are listed by soap opera, and soap operas by country of origin. The history of LGBT characters that feature in soap operas begins in Australia, with Don Finlayson, portrayed by Joe Hasham, who appeared in the Australian television soap opera Number 96 between 1972 and 1977.

Sos mi hombre is an Argentine telenovela, which aired on El Trece between August 2012 and June 2013.

Las Estrellas is an Argentine soap opera produced by Pol-Ka Producciones for El Trece between May 2017 and January 2018. Starring Celeste Cid, Marcela Kloosterboer, Natalie Pérez, Violeta Urtizberea, Justina Bustos, and co-starring, Esteban Lamothe, Gonzalo Valenzuela, Luciano Castro, Nicolás Riera, Nicolás Francella and Julieta Nair Calvo.

The Box is an Australian soap opera produced by Crawford Productions and broadcast by The 0-10 Network, which aired between February 1974 and October 1977.

Home and Away is an Australian television soap opera broadcast by Seven Network, which began airing in January 1988.

Neighbours is an Australian television soap opera, originally broadcast by Seven Network. The network dropped the show and it was picked up by Network Ten, which later aired it on Eleven. The serial began airing in March 1985. The show went on a year-long hiatus from 28 July 2022, following a cancellation, but was revived a few months later commissioned by Amazon, with the show airing locally on 10.

Number 96 is an Australian television soap opera broadcast by The 0-10 Network, which aired between March 1972 and August 1977.

The Power, The Passion is an Australian television daytime soap opera produced by the Seven Network in 1989.