Longfellow, also referred to as Greater Longfellow, is a defined community in Minneapolis, Minnesota which includes five smaller neighborhoods inside of it: Seward, Cooper, Hiawatha, Howe and Longfellow. The community is a mix of agri-industrial properties along the old Milwaukee Road now Minnesota Commercial Railway, expansive parkland surrounding the famous Minnehaha Falls, and smaller residential areas.

The city did not acquire land south of Franklin Avenue until 1881 and 1883, with the last half of Longfellow annexed in 1887 from Richfield. The area was largely built from 1906 through the 1920s when streetcar and residential rail became accessible. Also the advent of ready-to-assemble homes such as Sears Catalog Homes made homeownership accessible to the primarily immigrant population of the city who could not afford the carpentry or craftsmanship to build single-family homes (or mansions) of the era. Most of these early homeowners were first and second generation Scandinavians who moved out from Cedar Riverside. Even by 1930, the south area was still a major immigrant hub compared to the southwest area with a high foreign-born or second generation population.

Longfellow takes its name from Longfellow neighborhood which in turn is named after Henry Wadsworth Longfellow. The renowned American poet incorporated elements into his poem The Song of Hiawatha from Henry Schoolcraft's accounts of native Dakota lore in Minnesota which included Minnehaha Falls in Longfellow's southern tip. The early reference of Highway 55 as Hiawatha Avenue, along the west border, may have influenced the naming decision when community borders were drawn in the 1960s. Hiawatha Avenue is the main thoroughfare leading north into Downtown Minneapolis and south to the Minneapolis-Saint Paul Airport.

Longfellow's popular The Song of Hiawatha spurred national interest in Minnehaha Falls and his name became associated with the area. The poet's name would be further emphasized when the Longfellow House was built in 1906. A local businessman, Robert Fremont "Fish" Jones, commissioned the 2/3 scale replica of Henry Wadsworth Longfellow's original home in Cambridge, Massachusetts. The house was placed as part of the Longfellow Zoological Gardens at 4001 Minnehaha Parkway East, which Jones ran. Jones died in 1934 and the house was deeded to the city. For a short period it was a Minneapolis public library serving the community until it was moved and restored by the Park Board in 1994 to its current location near Minnehaha Falls. It is now an interpretive and information center for the Minneapolis Park System.

An unexplained South Minneapolis phenomenon called the Longfellow Boom, described by residents as "house-shakingly loud" and at lower tone, distinct from a car crash or gunshot, is named after the community.

The community was the center of widespread civil unrest during the George Floyd protests in Minneapolis–Saint Paul in May 2020, with the Minneapolis Police Department's third precinct station and many local businesses among those destroyed by arson.

The community is considered part South Minneapolis. It is bounded by the city's eastern border with the Mississippi River to the east, Hiawatha Avenue to the west, Hiawatha Avenue and the Metro Blue Line to the southwest/west, and Interstate 94 to the north. It is primarily located in Ward 12, represented by city council member Aurin Chowdhury. The Seward neighborhood is split between Ward 2 and Ward 6, represented by Robin Wonsley and Jamal Osman, respectively. Most of Greater Longfellow (with the exception of Seward) is represented by the Longfellow Community Council.

Longfellow is home to the Danish American Center, Minnehaha Academy, Christ Church and the Longfellow House. The area is typically recognized by bungalow style Craftsman homes built in the 1920s. It also contains the Ray and Kay Price House, designed by the famed Ralph Rapson, and the Frederick Lang House, designed by Herb Fritz. Minnehaha Falls is a national attraction and an important cultural node of the Twin Cities.