Following her marriage, Louisa quickly began having children. This period likely involved a demanding workload of childcare and domestic duties in a rural environment. She and Peter moved frequently as he sought work in the goldfields.

Louisa gave birth to her son, Henry Lawson, who would later become one of Australia's most renowned writers. Louisa had a profound influence on Henry's literary development.

Louisa had five children in total with Peter Lawson: Henry, Charles, Peter, Gertrude and Isabel. This period represented a significant commitment to motherhood and family responsibilities, placing considerable strain on her physical and emotional well-being.

The marriage between Louisa and Peter Lawson began to deteriorate. Peter's absence and struggles to provide for the family placed a considerable strain on their relationship. Financial difficulties and Peter's increasingly erratic behaviour caused great distress.

After years of hardship, Louisa separated from Peter Lawson. This decision was a significant step towards independence, but it also brought financial uncertainties and the responsibility of raising her children as a single mother.