Rashford made his first-team debut for Manchester United in the UEFA Europa League against Midtjylland, scoring two goals in a 5–1 win.

Rashford made his Premier League debut against Arsenal, scoring twice and providing an assist in a 3–2 home victory.

Rashford scored the only goal in the Manchester derby, becoming the youngest scorer in the fixture in the Premier League era.

Rashford won his first FA Cup with Manchester United, defeating Crystal Palace 2–1 in the final.

Rashford won the UEFA Europa League with Manchester United, defeating Ajax 2–0 in the final.

Rashford signed a new four-year contract with Manchester United, keeping him at the club until June 2023.

Rashford scored his 100th goal for Manchester United in a 1–0 win against West Ham.

Rashford won the EFL Cup with Manchester United, defeating Newcastle United 2–0 in the final.