List of General Hospital characters introduced in the 1960s

General Hospital is the longest running American television serial drama, airing on ABC. Created by Frank and Doris Hursley, who originally set it in a general hospital (hence the title), in an unnamed fictional city. In the 1970s, the city was named Port Charles, New York. The series premiered on April 1, 1963. This is a list of notable characters who significantly impacted storylines and began their run, or significantly returned, from the years 1963 to 1969.

Thomas "Tom" Baldwin is a fictional character from the ABC Daytime soap opera, General Hospital. The role was originated by Paul Savior in 1966. The character was presumably killed off in 1972, but brought back on canvas in September 1976, portrayed by Don Chastain, who left in 1977 amongst a large number of cast changes that occurred when Irving and Tex Elman took over as head writers.

Tom Baldwin joined General Hospital in December 1966 to replace Dr. Peter Lindsay. Tom soon became interested in Jessie Brewer, R.N. but Jessie was in a relationship with Dr. John Prentice. Dr. Prentice's daughter, Polly, was also interested in Tom. In 1967, Tom Baldwin is treating Dr. John Prentice for his heart condition when John dies. When it is revealed that John had died because of a barbiturate overdose, John's daughter Polly Prentice tries to frame Jessie Brewer for murder. Tom is charged as an accessory before Phil Brewer returns to town with evidence that clears them both. Meanwhile, nurse Audrey March returns from Vietnam, trying to forget about her divorce from Steve Hardy, and marries Tom. When Audrey refuses to sleep with him, Tom is furious and rapes Audrey. When Audrey learns she is pregnant, she files for divorce and leaves town.

In 1972, Audrey returns, claiming the baby had died so that Tom would not protest the divorce. Audrey and Steve decide to remarry, but the lies Audrey was telling begin to hurt their relationship and they break up. Tom finds out about the baby and tries to get custody. Audrey is forced to stay in their marriage, and they rename the baby Tom "Tommy" Baldwin Jr. When their relationship ends, Tom leaves the country with the child, with the help of Florence Andrews. Eventually, the child is sent back to Audrey, who is told that Tom died of a heart attack.

In September 1976, Tom is revealed to be alive and returns to fight for custody of the child, while begging Audrey not to divorce him. When Tommy runs away, Tom agrees to the divorce and moves to Salt Lake City. Audrey and Steve remarry while Steve adopts Tommy, renamed Tom Hardy.

Meg Baldwin (also Quinton and Bentley) is a fictional character from the ABC Daytime soap opera General Hospital. Patricia Breslin originated the role in 1965. Jen Shepard temporarily portrayed the character from June 27 to July 19, 1967, when Breslin had an emergency appendectomy. Breslin left in 1969 when she married Art Modell. The role was taken over by Elizabeth MacRae, in August 1969, who left the series when the character died in 1973.

In 1965, Meg Bentley becomes a nurse at General Hospital. Her husband Lloyd has just died and she moves to town with her son Scotty and stepdaughter Brooke. Meg is engaged to Dr. Noel Clinton, which Brooke does not approve of. Brooke seduces Noel away from Meg, and Meg is comforted by Lee Baldwin. Soon they are married. In 1969, Meg learns she has breast cancer and has a radical mastectomy. After the mastectomy, Meg has a mental breakdown and has to be committed to a sanitarium. She is eventually cured, but seeks treatment from Dr. Lesley Webber for high blood pressure. Meg dies, and Lee adopts Scotty.

Angie Costello Collins (formerly Weeks) is a fictional character from the ABC Daytime soap opera, General Hospital. Jana Taylor originated the role on the series' premiere on April 1, 1963. Taylor portrayed the role until September 22, 1966. She returned for a guest appearance on the show's 30th anniversary episode on April 1, 1993.