While specific details of Meguey Baker's early life are not widely publicized, it's known that her formative years fostered a love for storytelling and creative expression. Her later work as a quilt historian suggests an early appreciation for material culture and the stories embedded within handcrafted objects. These combined interests lay the groundwork for her eventual career in game design, where narrative, mechanics, and thematic resonance are paramount.

Meguey Baker began making waves in the burgeoning indie RPG scene. This period saw her active participation in online forums and communities dedicated to alternative and narrative-focused game design. Her early contributions highlighted a desire to move beyond traditional dungeon-crawling mechanics and explore more character-driven and emotionally resonant gameplay experiences.

The release of "The Pool", co-designed with Emily Care Boss, marked a significant breakthrough. "The Pool" is a GM-less, narrative-focused RPG emphasizing player agency and improvisational storytelling. Its innovative dice pool mechanic, where success is determined by comparing pools of dice controlled by each player, provided a framework for shared narrative control that was relatively novel at the time. "The Pool" helped define a new wave of indie RPG design and solidified Meguey Baker's reputation as an innovative voice.

Following the success of "The Pool", Meguey continued to design and independently publish RPGs, often in collaboration with her partner, Vincent Baker. This period showcased her commitment to fostering a supportive and inclusive design environment within the indie RPG scene. Her work helped create a space where experimental mechanics and diverse perspectives could thrive, allowing more people to see themselves in the hobby.

Although Vincent Baker is credited as the primary designer, Meguey Baker's contributions to "Apocalypse World" were significant. This game became a landmark title, popularizing the 'Powered by the Apocalypse' (PbtA) system. The emphasis on player choice, emergent storytelling, and defined character playbooks had a profound impact on the RPG landscape. "Apocalypse World" established a new standard for indie game design and spurred the creation of countless derivative works and inspired games.

Following the release of "Apocalypse World", Meguey continued to contribute to the PbtA ecosystem and design other games, often in collaboration with Vincent. Her work focused on exploring different genres and themes, always with an emphasis on character agency and compelling narratives. She maintained a strong presence within the indie RPG community, mentoring aspiring designers and championing diverse voices within the industry.

Alongside her RPG design work, Meguey Baker has pursued her passion for quilt history. She combines her historical research with her creative pursuits, showcasing the rich narratives embedded within textile arts. This dual focus demonstrates a commitment to both historical preservation and artistic innovation, reflecting a holistic approach to storytelling across different mediums.