The Middle Tennessee Blue Raiders football is the intercollegiate football program representing Middle Tennessee State University in Murfreesboro, Tennessee. The Blue Raiders compete in the Football Bowl Subdivision (FBS) of the National Collegiate Athletic Association (NCAA) and are a member of Conference USA. They are coached by Derek Mason, who was hired as the 15th head coach in program history on December 6, 2023.

Middle Tennessee has appeared in 14 bowl games and seven I-AA playoffs. The Blue Raiders play their home games at the Johnny "Red" Floyd Stadium, which has a seating capacity of 27,303.

Middle Tennessee State University first fielded a football team in 1911 under the direction of head coach L. T. "Mutt" Weber. They won their first game in 1912. From 1913 to 1923, Alfred B. Miles led the Blue Raiders football program. The 1914 football season led by Miles was its first undefeated season, with five straight victories after a tie with Cumberland.

Frank Faulkinberry was hired as MTSU's head coach after Miles' departure. During his tenure, the Blue Raiders compiled a record of 33–26–4. Faulkinberry was found shot to death in his garage on May 13, 1933, a suspected suicide being the cause.

E. M. Waller led the Blue Raiders for two seasons and compiled a 3–14–1 record. Waller resigned due to the team's struggles after two seasons.

Johnny Floyd started coaching MTSU in 1935 and led the Blue Raiders for four seasons. Under his tutelage, the Blue Raiders compiled a record of 30–8–1. Floyd's 1935 team went a perfect 8–0. However, a 2–6 campaign in 1938 ended his time in Murfreesboro.

Ernest Alley was named the next head coach of MTSU football, and in his one-season, the Blue Raiders compiled a 1–6–1 record.

Elwin W. Midgett led the Blue Raiders for four seasons (MTSU did not field a football team from 1943 to 1945 because of World War II. In 1940, Midgett led the Blue Raiders to a 4–4 mark. In 1941, the Blue Raiders posted a 4–3–1 campaign, followed by 4–2–1 in 1942, and 6–2–1 in 1946.